For Physicians · Lead Clinical Adopters

Practice medicine at the upstream.

An invitation to the first 100 founding Filipino physicians treating mitochondrial dysfunction and inflammaging — with measurement, not guesswork.

Request the program brief
01 What you’d practice

Inflammation you can read — and act on early.

The GLIS composite turns routine lab markers into one upstream signal — so you can act before downstream conditions take hold.

Upstream framing

Read inflammation with GLIS, before it becomes a labelled condition.

Filipino-authored, global-standard science

Co-developed with MSU-IIT and MERAV, registered with the FDA.

Clinical dosing guidance

A structured protocol and doctor-facing tools, not a sales script.

A founding circle

Among the first 100 licensed Filipino physicians practising at the upstream.

02 The recovery rationale

A layered recovery system — not just a probiotic.

SynBIOTIC+ pairs a spore-forming probiotic with prebiotic, postbiotic and antioxidant layers — a layered design, uncommon among probiotics, positioned as post-antibiotic gut and cellular recovery. Described as support, not the treatment or prevention of any disease.

Prebiotic

FOS (fructo-oligosaccharides)

Feeds beneficial microbes and supports recolonisation of the gut after antibiotic exposure.

Probiotic

Spore-forming Bacillus coagulans (LactoSpore®)

Its spore coat survives gastric acid to reach the gut, helping restore microbiome balance and resilience during and after antibiotics. Similar Bacillus and multi-strain formulations have shown benefit in antibiotic-associated diarrhoea1, with modulation of gut microbiota and inflammatory cytokines2; broader meta-analyses report a reduced risk of C. difficile-associated diarrhoea in patients receiving antibiotics3.

Postbiotic

Urolithin-A + L-Tryptophan

Urolithin-A supports mitochondrial renewal (mitophagy); L-tryptophan is a precursor in gut–immune and gut–brain signalling — extending recovery from the microbiome to cellular energy.

Antioxidant

Glutathione + Lutein

Help buffer the oxidative stress that accompanies inflammation and tissue repair.

  1. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012;307(18):1959–1969. doi:10.1001/jama.2012.3507
  2. Madempudi RS, Ahire JJ, Neelamraju J, Tripathi A, Nanal S. Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel syndrome in adults. Scientific Reports. 2019;9:12210. doi:10.1038/s41598-019-48554-x
  3. Goldenberg JZ, Yap C, Lytvyn L, et al. Probiotics for the prevention of Clostridioides difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews. 2017;12:CD006095. doi:10.1002/14651858.CD006095.pub4
Research and registration
FDA
Registered · CPR FR-400…456
USAID
Funded research
MSU-IIT
Co-developed R&D
19
Branches nationwide
80B
CFU · 17 strains
The founding 100

Read the inflammation. Practise the upstream.

Request the LCA program brief and clinical dosing guidance for licensed Filipino physicians.

Request the program brief

Honest by design.

We describe support for inflammation and recovery without presenting SynBIOTIC+ as a treatment or cure. Consult a licensed physician for personal health decisions.